Derrynane House is a 19th-century house located in County Kerry, Ireland. It is the ancestral home of Daniel O'Connell (1775 – 1847), known as ‘The Liberator’ and a prominent Irish politician. 

The house is now a museum dedicated to his life and works and contains a collection of O'Connell's personal artifacts, including furniture, books, and paintings, as well as a library and a museum of Irish history.

The house is set on the grounds of Derrynane National Historic Park, which includes a beach, gardens, and nature trails. The house has been restored to its original state and is managed by the Office of Public Works. It is open to the public for guided tours and is a popular tourist attraction.